The University of California, Davis, School of Medicine, Department of Dermatology, is recruiting for a full-time academic position in the Project Scientist series at the Associate level based on experience and qualifications.
The Project Scientist makes significant and creative contributions to a research or creative project in his/her academic discipline. The appointee possesses the subject matter expertise and the creative energy necessary to function at a high level of competence. The appointee will participate in activities to increase, improve, or upgrade competency. Appointees with Project (e.g., Scientist) titles may engage in University and public service. They do not have teaching responsibilities. Although the Project Scientist is expected to work independently under the general guidance of an academic member with an independent research program (i.e., Professor, Professional Researcher, Specialist in Cooperative Extension, etc.), he/she is not required to develop an independent research program or reputation. He/she will carry out research or creative programs with supervision by an individual in an academic title that carries with it automatic Principal Investigator status. The Project Scientist does not usually serve as a Principal Investigator but may do so by exception.
Research for this position focuses tumorigenesis of oncogenic viruses. The appointee must possess expertise in cancer research and have “hands-on” experience in the areas of tumor stroma, tumor microenvironment, angiogenesis, and inflammation. In particular, the appointee must demonstrate strong skills in the analysis of tumor associated macrophages (TAMs) and myeloid-derived suppressor cells (MDSCs). In addition, the appointee must be very familiar with the biology of oncogenic viruses such as Kaposi’s sarcoma-associated herpesvirus (KSHV), and proficient with modern molecular and cellular biology technologies as well as small animal handling.
• Ph.D. in Medicine or in an equivalent Scientific Field of Study.
• Must have at least three years of molecular and biochemical studies in cancer biology.
• The candidate should have significant experience in cancer virology as demonstrated by first or senior author publications.
• The candidate should have a record of developed skill sets in mentoring junior researchers, writing manuscripts and grants, and oral presentations.
• The candidate should have the ability to work cooperatively and collegially in a diverse environment.
RESPONSIBILITIES AND DUTIES:
I. RESEARCH (80%):
This position requires creative contributions to and collaborative development of active research programs that are aimed to understand the biology of tumor stroma in the context of oncogenic viral infection and explore the potential of targeting tumor stroma cells including TAMs and MDSCs for cancer therapy. The candidate will help to determine and define the unique and “virus-specific” tumor stroma cell types, particularly TAMs and MDSCs, for their contribution to virus-induced tumor initiation, angiogenesis, anti-tumor immune suppression, and tumor progression, in consultation with the Principal Investigator (PI), Dr. Yoshihiro Izumiya. The candidate will use global genomic, epigenetic, and proteomic analyses to decipher the molecular mechanisms of virus induced TAMs and MDSCs and identify unique molecular markers for such unique tumor stroma cell types. By using small animal models and nanotechnologies, the candidate will also examine the therapeutic potentials of targeting TAMs and/or MDSCs. In addition, the candidate will determine contributions of viral replication, particularly reactivation of latent viruses associated with bacterial infection or other types of conditions such as diabetes and chronic inflammation, to the generation of TAMs and MDSCs and tumor progression. Finally, in collaboration with clinicians, the candidate will collect patient samples to further examine the association of TAMs and MDSCs with virus-induced tumor development. He/she will design specific research strategies and plans, including the selection of appropriate methods and techniques. The candidate may advise students or technicians regarding the technical aspects of the research, including methods development, trouble-shooting problems, interpreting results, and planning follow-up experiments.
II. PUBLICATION AND GRANT ACQUISITION (10%)
He/she will publish research results in peer-reviewed journals, books, and other outlets either independently or in collaboration with the PI or other members of the research team, and assist in acquiring proposals for funding from federal and state agencies and other funding organizations. The candidate will prepare and assist in the preparation of reports as required by granting agencies. The candidate will interact with funding agencies and prepare modifications of budgets and other grant components as needed.
III. PROFESSIONAL COMPETENCE AND ACTIVITY (10%):
The candidate will participate in professional societies and conferences appropriate to his/her specific field and will serve as a reviewer of research proposals and scientific publications as appropriate. The candidate will attend seminars to present research results and may give oral presentations to public and professional interest groups. When appropriate, the candidate may coordinate and/or give presentations at seminars, laboratory meetings or educational functions.
Applications should be received by September 16, 2018, for primary consideration; however, the position will be open until filled through June 30, 2019. The following information is required: Cover Letter, Curriculum Vitae and Statement of Contributions to Diversity. Please visit http://academicaffairs.ucdavis.edu/diversity/equity_inclusion/index.html for information about why diversity statements are requested and guidelines for writing a diversity statement.
Please upload this information and apply online at https://recruit.ucdavis.edu/apply/JPF02351.
The position is located in Sacramento, California. The Department of Dermatology (http://www.ucdmc.ucdavis.edu/dermatology/) is a major clinical care, research, and teaching Department in the School of Medicine. Our faculty is engaged in multiple collaborations with other Schools and UC Davis campus departments, research centers, clinical centers, and primary care networks, and thus all positions require flexibility in local job locations in addition to the Department of Dermatology. This includes the Veteran’s Administration, UCD Medical Center Campus, and other community centers.
UC Davis commits to inclusion excellence by advancing equity, diversity, and inclusion in all that we do. We are an Affirmative Action/Equal Opportunity employer, and particularly encourage applications from members of historically underrepresented racial/ethnic groups, women, and individuals with disabilities, veterans, LGBTQ community members, and others who demonstrate the ability to help us achieve our vision of a diverse and inclusive community. For the complete University of California nondiscrimination and affirmative action policy see:
http://policy.ucop.edu/doc/4000376/NondiscrimAffirmAct. If you need accommodation due to a disability, please contact the recruiting department. Under Federal law, the University of California may employ only individuals who are legally able to work in the United States as established by providing documents as specified in the Immigration Reform and Control Act of 1986. Certain UCSC positions funded by federal contracts or sub-contracts require the selected candidate to pass an E-Verify check. More information is available http://www.uscis.gov/e-verify. UC Davis is a smoke & tobacco-free campus (http://breathefree.ucdavis.edu/).
Curriculum Vitae - Your most recently updated C.V.
Statement of Research (Optional)
Statement of Teaching (Optional)
Statement of Contributions to Diversity - Diversity contributions documented in the application file will be used to evaluate applicants. Visit http://academicaffairs.ucdavis.edu/diversity/equity_inclusion/index.html for guidelines about writing a diversity statement and why one is requested.