UC DAVIS GENOME CENTER
Supervisor: Dr. David Segal
In direct collaboration with the Principal Investigator(s), this position will be involved in the Angelman syndrome research project, which focuses on developing therapeutics based on gene and epigenome editing tools to treat Angelman syndrome and related neurologic disorders.
The candidate will specifically participate in the development and testing of novel molecular constructs based on zinc fingers, TALEs, or CRISPR/Cas9 to cause persistent epigenetic changes in gene expression. The constructs will be tested in cell and animal models of Angelman syndrome. As a member of the research team, work will include construction of molecular clones, RT-qPCR, Westerns, DNA Sequencing (Sanger and next-generation sequencing), ChIP-PCR, bisulfite sequencing, and cell culture.
The candidate will prepare manuscripts for publications, in collaboration with her/his direct supervisor. Manuscript preparation by the candidate will include reviewing the relevant literature and summarizing these reviews in the introduction, describing results and methods used to acquire the results, presenting and analyzing data obtained by the candidate, constructing clear and informative figures, interpreting the results and discussing how they fit in the current understanding of the field. Depending on whether the candidate is first or middle author of the manuscript in preparation, she/he will contribute these items for most of the manuscript or only the part contributed.
Professional Competence (10%)
Depending on interest and availability of funds, the Junior Specialist will have opportunities to present research findings to a larger audience at scientific conferences or meetings. The candidate will also assist the investigator in presenting progress reports and final summaries to granting agencies.
University and Public Service (5%)
The Junior Specialist will participating in training activities, such as mentoring undergraduate students. They will actively contribute to lab activities via meetings and unit/campus presentations.
Interested candidates should submit all materials via the web-based online submission system (https://recruit.ucdavis.edu/), JPF01853. Required materials include a cover letter, curriculum vitae, statement of research, and names and contact information for three references. The deadline for full consideration is October 6, 2017.
Curriculum Vitae - Your most recently updated C.V.
Statement of Research
Statement of Teaching (Optional)
Statement of Contributions to Diversity - Diversity contributions documented in the application file will be used to evaluate applicants. Visit http://academicaffairs.ucdavis.edu/diversity/equity_inclusion/index.html for guidelines about writing a diversity statement and why one is requested.
- 3 references required (contact information only)