The Department of Pathology and Laboratory Medicine at the University of California, Davis invites applications for a qualified Junior Specialist.
This position will involve working on interdisciplinary studies focusing on questions in pharmacokinetic and pharmacodynamic (PK/PD) modeling of drugs for dose individualization approaches in critically ill patients, as well as questions in point of care testing. The Junior Specialist will work directly with the PI, study coordinator, and other lab members to refine study design and determine study feasibility for new research investigations. These tasks apply to all studies conducted in the lab. More specifically, the Junior Specialist’s primary focus will be to work with the PI to begin looking at the PK/PD parameters of fentanyl dosing in the adult burn intensive care unit (ICU) population. It is expected that the Junior Specialist will conduct a thorough literature review of PK/PD studies including but not limited to fentanyl administration to critically ill patients, the pathophysiology of a burn injury, and burn specific drug metabolism. In conducting the study, the Junior Specialist will determine sample collection schematics from patients, coordinate sample collection with hospital staff, and submit patient samples for quantification of fentanyl concentrations. The position will involve analysis of the resulting data by PK/PD modeling software (Monolix, MATLAB, etc.) and preparation of results for abstract and/or manuscript publication. It is expected that the Junior Specialist will work with members of the lab as well as local experts in the field to prepare a manuscript for submission to a peer reviewed journal for this study and others that arise during the employment period. This position requires creative thinking and problem solving in all aspects of work, as well as excellent communication and the ability to work in a chaotic environment such as an ICU.
In addition, the Junior Specialist will serve as a mentor to summer interns, undergraduate members of the lab, and high school student volunteers.
Successful candidates will also participate in clinical research studies involving new investigational drugs and/or devices.
General responsibilities include:
The position of Junior Specialist has a narrow focus in a specialized area and provides technical or specialized expertise (e.g., with instrumentation and research equipment, or with research methods) in the planning and execution of a research project. For this position, the Junior Specialist will be responsible for learning and using PK/PD modeling software to analyze results from the burn ICU fentanyl study, and will also learn point of care testing techniques for instruments measuring different analytes (i.e. glucose, lactate, and troponin). Consent of human subjects for clinical research will be tasked to the Junior Specialist, which requires excellent communication and comfort in potentially stressful situations. In addition, the Junior Specialist will be required to review journal articles involving the PK/PD of fentanyl and factors that can influence metabolism, such as injury and genetic polymorphisms, and will be expected to stay up to date on current literature from any additional projects they are participating in. The position will involve engaging in discussions with the PI on the research and the interpretation of research results. This open line of communication will be essential for the PK/PD study, as it will be the primary project for the Junior Specialist. If the opportunity arises it is also expected that the Junior Specialist will attend professional meetings to present results as a poster or oral presentation. Mentorship is an important part of the Junior Specialist position and will involve orientating undergraduates, interns, and volunteers to the lab, providing advice on study design, assisting with data collection/analysis, and reviewing presentations. This position will also involve review and editing of research proposals, grants, journal manuscripts, and abstracts prepared by the PI other member of the lab on varying topics.
The ideal candidate will have strong interpersonal, communication, and decision-making skills; as well as the ability to work well independently and as part of a team.
Ability to quickly gain knowledge and understanding to efficiently and effectively learn and perform the following tasks:
•Manage complex medical and clinical data and accurately enter them into Case Report Forms and/or databases.
•Efficiently and effectively operate laboratory equipment and prepare laboratory samples, including hazardous biological specimens (e.g. blood, sputum).
•Follow broadly defined instructions and complete experimental procedures in accordance to relevant protocols.
•Perform new technical laboratory procedures with minimal or no supervision.
•Follow institutional safety guidelines when processing human specimens, using biological safety cabinets, and using protective clothing (latex gloves, laboratory coat, face mask, eye protection), and follow specific detailed instruction on the safe handling of biohazardous material.
•Develop an understanding of disease processes and therapies pertaining to specific research projects (e.g. sepsis, pathophysiology of burn injury).
•Prepare regulatory documentation for Institutional Review Boards.
•Perform all work in adherence to study protocols.
•Follow the regulatory requirements of the F.D.A., N.I.H., Institutional Review Board, Office of Human Research Protection, UCD research policy and procedures, and appropriate regulatory agencies.
•Assist with clinical trial subject recruitment and tracking.
•Plan and conduct biological sample collections from different sources, and prepare such samples for shipment as appropriate per IATA/DOT regulations.
•Organize and prioritize the workload requirements.
•Keep clear and accurate records and provide timely reports, and work on several projects simultaneously.
•Demonstrate knowledge of safety requirements and regulations pertaining to the research, teaching and administrative functions of the department.
•Aid in monitoring compliance to federal regulations governing research.
•Communicate effectively with general public, physicians, patients, and other health care professionals on matters pertaining to the research at hand.
•Bachelor degree in biomedical engineering or a related field with previous laboratory course experience.
• Have basic level understanding of Biological Sciences
• Have demonstrated proficiency with bench science activities, including but not limited to: dilution preparation, specimen handling, accurate measuring of chemicals, etc.
• Have demonstrated proficiency with PK/PD modeling software (Monolix, MATLAB, etc.) or experience in similar software.
• Posses the ability to respond timely to email and voicemail messages.
• The ability to be able to function in a loud, hectic environment
• Be able to be attentive and reliable with various modes of communications (email, calls, texts, etc.)
• Possess good inter-personal skills and be capable of working with a variety of personalities
• Have a car or other reliable transportation
Step I - $18.26 hourly or Step II - $19.48 hourly, commensurate with qualifications and experience.
Number of Positions Available: 1
Term Of Appointment:
Short-term 1-year maximum Non-Exempt appointment, seasonal appointment based on the needs of the research project. Appointments may be made up to 100%.
This posting will remain open until filled through June 30, 2018.
Applicants should submit Cover Letter (Optional), CV or Resume, Contact Information for three references (Required), and 3 letters of recommendations (Optional) at https://recruit.ucdavis.edu/apply/JPF01775.
All letters will be treated as confidential per University of California policy and California state law.
QUESTIONS: Please direct questions to Vadim Gol at firstname.lastname@example.org.
UC Davis commits to inclusion excellence by advancing equity, diversity and inclusion in all that we do. We are an Affirmative Action/Equal Opportunity employer, and particularly encourage applications from members of historically underrepresented racial/ethnic groups, women, individuals with disabilities, veterans, LGBTQ community members, and others who demonstrate the ability to help us achieve our vision of a diverse and inclusive community.
Under Federal law, the University of California may employ only individuals who are legally able to work in the United States as established by providing documents as specified in the Immigration Reform and Control Act of 1986. Certain UCSC positions funded by federal contracts or sub-contracts require the selected candidate to pass an E-Verify check. More information is available http://www.uscis.gov/e-verify.
UC Davis is a smoke & tobacco-free campus (http://breathefree.ucdavis.edu/).
If you need accommodation due to a disability, please contact the recruiting department.
Curriculum Vitae - Your most recently updated C.V.
Cover Letter (Optional)
Statement of Research (Optional)
Statement of Teaching (Optional)
Statement of Contributions to Diversity - Diversity contributions documented in the application file will be used to evaluate applicants. Visit http://academicaffairs.ucdavis.edu/diversity/equity_inclusion/index.html for guidelines about writing a diversity statement and why one is requested. (Optional)
Recommendation Letter #1 (Optional)
Recommendation Letter #2 (Optional)
Recommendation Letter #3 (Optional)