INTRODUCTION: The Laboratory of Pesticide and Biotechnology is housed in Entomology and Nematology. The team of over 30 scientists and students employ a multidisciplinary, integrated approach to research that delves into basic questions of biology and biochemistry that have practical implications for improving both human health and environment.
The work in the lab is focused on four areas: 1) regulatory and developmental biology using insect and mammalian systems; 2) mammalian enzymology – the study of enzymes involved in foreign compound metabolism and their possible endogenous roles; 3) analytical chemistry - developing rapid analytical methods for metabolomics and detecting environmental contaminants and 4) development of pharmaceuticals to treat pain.
The laboratory is the home of the UC Davis/NIEHS Superfund Basic Research and Training Program. The historical research funding base is diverse and includes long terms grants from NIEHS, NIOSH, NINDS, NIDDK, NCI, the American Asthma Foundation and many private and research foundation contracts and grants.
NATURE AND PURPOSE
The Assistant Research Scientist develops and oversees their own independent research program making significant and creative contributions to a research his/her academic discipline equivalent to that required for the Professor series. The appointee possesses specialized knowledge in soluble epoxide hydrolase biochemistry and pain physiology in mammals including the subject matter expertise and takes major responsibility and leadership for his/her programs. Appointees do not have teaching responsibilities. He/she will apply for independent funding and may be funded as a co-PI within a large center or collaborative program grant on which many independent investigators are working.
Research Activity (60%)
Under the direction of Dr. Bruce Hammock, the candidate will devise and conduct studies in development of an active research program(s) in the fields of pharmacology and regulatory biology with particular emphasis on the use of in vivo models of pain, inflammation and neuroinflammatory disorders to analyze physiological and pharmacological discoveries. The candidate will be key personnel on several federally funded research grants and write independent grants for additional funding involving the use and development of new methods for exploring the role of soluble epoxide hydrolase (sEH), sEH inhibitors, and dietary omega-3 fatty acid supplementation in the modulation of epoxy fatty acid metabolism in disease states. The position will require the candidate to take a leadership role in animal studies and collect, summarize and analyze data from experiments that will involve survival surgeries for drug delivery as well as pharmacokinetic (PK) analysis of sEH inhibitors in different animal models. The candidate will investigate fundamental mechanisms of neurological disorders. These studies will also involve the optimization of formulation and delivery methods of sEH inhibitors as needed.
The candidate will prepare reports on research findings, publish research results as senior author in peer reviewed publications, either independently or in collaboration with the PI and other members of the research team.
Grant Acquisition (10%)
The candidate may serve as a Principal Investigator to acquire funding as well as contribute to the development of collaborative grant proposals for funding from appropriate agencies and prepare reports as required by funding agencies.
PROFESSIONAL COMPETENCE AND ACTIVITY (15%)
The candidate will interact with the laboratory research group and students, communicate research data and results orally and in writing, conduct presentations of research at scientific meetings. He/She will train and advise predoctoral graduate students and postgraduate researchers within the department on their substantive research problems related to experimental design and implementation. Other duties will include organization of seminars and lab presentations when appropriate and reviewing research proposals, journal manuscripts, and publications.
UNIVERSITY AND PUBLIC SERVICE (5%)
The candidate will engage in public outreach activities that include presenting scientific research results to the general public and providing relevant advice to individuals or public agencies.
Requirements: Doctorate or equivalent in pharmacology, biochemistry or related field. Skills and expertise in the design and performance of animal studies including optimization of pharmacological intervention, survival surgery and dietary manipulation. Familiarity with LC-MS/MS sample preparation development and analysis. Demonstrate an ability to prepare and present research results in a variety of formats including scientific manuscripts for peer reviewed journals, abstracts, oral presentations to colleagues and collaborators and reports to research sponsors.
UC Davis is an affirmative action/equal employment opportunity employer and is dedicated to recruiting a diverse faculty community. We welcome all qualified applicants to apply, including women, minorities, veterans and individuals with disabilities.
UC Davis is a smoke- and tobacco free-campus effective January 1, 2014. Smoking, the use of smokeless tobacco products and the use of unregulated nicotine products (e-cigarettes) will be strictly prohibited on any property owned or leased by UC Davis -- indoors and outdoors including parking lots and residential spaces.
Curriculum Vitae - Your most recently updated C.V.
Cover Letter (Optional)
Statement of Contributions to Diversity - Diversity contributions documented in the application file will be used to evaluate applicants. Visit http://academicaffairs.ucdavis.edu/diversity/equity_inclusion/index.html for guidelines about writing a diversity statement and why one is requested.
- 3-5 required (contact information only)