Director of Medicinal Chemistry
Open date: March 30, 2023
Most recent review date: Wednesday, May 31, 2023 at 11:59pm (Pacific Time)
Applications received after this date will be reviewed by the search committee if the position has not yet been filled.
Final date: Monday, Jul 31, 2023 at 11:59pm (Pacific Time)
Applications will continue to be accepted until this date, but those received after the review date will only be considered if the position has not yet been filled.
Director of Medicinal Chemistry
The Institute of Psychedelics and Neurotherapeutics (IPN) at the University of California, Davis, is seeking a Director of Medicinal Chemistry to join our team. This position will be housed in the Department of Chemistry in the Professional Researcher series (Academic Federation) with rank and salary commensurate with experience.
Professional Research series: The Professional Researcher develops and oversees their own independent, creative, and high-quality research program equivalent to that required for the Professor series. The Professional Researcher takes major responsibility and leadership for their programs. Generally, the appointee is expected to secure funding as a Principal Investigator, but may be funded as a co-PI within a large center or collaborative program grant on which many independent investigators are working, as long as it is clear that the activities led by the professional researcher within the larger project constitute his/her own independent research program. Appointees do not have teaching responsibilities. University and Public Service are expected at the Associate/Full ranks (e.g. committee service, guest lecturing, public outreach, managing departmental facilities, involvement in government and/or professional society committees, etc.)
Responsibilities of the Director of Medicinal Chemistry:
· Work with the institute’s director and associate director to achieve the goals of the IPN and build a highly visible, world-class research program in neuropharmacology and CNS therapeutic development
· Serve as the leader of the medicinal chemistry team within the IPN
· Work with the Director of Pharmacology to identify lead candidates for a variety of indications
· Collaborate with IPN affiliated principal investigators and their trainees
· Oversee multiple concurrent research programs, both internal projects and collaborative projects with external academic and industrial partners
· Lead the synthetic chemistry programs for both internal projects and collaborative projects with pharmaceutical industry partners
· Manage the design, planning, and execution of synthetic strategies to access key target molecules
· Perform structure-activity relationship (SAR) studies as needed
· Utilize structure-based drug design when appropriate
· Evaluate pharmacological data to drive SAR
· Maintain equipment necessary to synthesize and characterize target compounds
· Work with the Director of Pharmacology to maintain a proprietary UC Davis compound library and associated databases
· Oversee the safety of IPN laboratories
· Supervision and mentoring of the staff and trainees within the IPN medicinal chemistry team
· Develop new research projects and play a major role in writing grant proposals proposals and securing funding from federal, state, private, and industrial sources
· Publish research results in high impact peer-reviewed journals
· Work with UC Davis Innovation Access and attorneys to file patents to protect UC Davis intellectual property
· Help initiate, evaluate, and implement IPN pilot grants
· Prepare reports and manage data rooms during diligence with potential industrial partners interested in licensing IPN technology
· Other activities may include managing project budgets, supervising employees, writing and submitting progress reports to funding agencies, presenting at conferences, participation in professional societies, and reviewing grants and manuscripts.
· Ph.D. in chemistry, medicinal chemistry, or a related field
· Have a minimum of 5 years of postdoctoral or industry experience beyond the Ph.D.
· Outstanding background in synthetic chemistry with demonstrated aptitude for problem solving in medicinal chemistry
· Have a demonstrated track record of leading key aspects of drug development programs with a deep understanding of the underlying science.
· Demonstrated strong organizational skills
· Excellent written and oral communication skills
· An outstanding record of leadership or potential for leadership in research
· Evidence of research or creative activities of high quality, innovation, and significance
· Industrial experience developing small molecule therapeutics
· Experience performing IND-enabling studies
· Expertise in the development of therapeutics for central nervous system disorders
Curriculum Vitae - Your most recently updated C.V.
Statement of Research (Optional)
Statement of Contributions to Diversity, Equity, and Inclusion - Contributions to diversity, equity, and inclusion documented in the application file will be used to evaluate applicants. Visit https://academicaffairs.ucdavis.edu/faculty-equity-and-inclusion for guidelines about writing a statement and why one is requested.
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